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@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
UK HR+/HER2- BREAST CANCER KOL MAPPING

One five-centre South West England consortium tracks 666 UK patients across all three approved CDK4/6 inhibitors. The UK's HR+/HER2- metastatic breast cancer KOL...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
UK HR+/HER2- BREAST CANCER HTA STRATEGY MODEL

NICE accepts all three CDK4/6 inhibitors as comparators for each other, but none has ever faced exemestane plus everolimus head-to-head. NICE's technology...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US NSCLC FIELD FORCE STRATEGY

NSCLC's prescriber base is roughly 13,000 US oncologists, concentrated enough that account depth, not reach, decides field strategy. NSCLC is prescribed almost...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US TYPE 2 DIABETES DISEASE LANDSCAPE

38.4 million US adults have diabetes, 8.7 million undiagnosed, and complication burden like CKD is now redrawing the treatment pathway around organ protection....

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US SPINAL MUSCULAR ATROPHY DISEASE LANDSCAPE

SMN2 copy number sets SMA severity from Type 1 to Type 4, and newborn screening finds about 300 US infants a year before symptoms appear. Spinal muscular atrophy...

@moatrx • 2 weeks ago

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@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
UK SPINAL MUSCULAR ATROPHY DISEASE LANDSCAPE

Among newly diagnosed UK Type 2/3 SMA patients under 18, 65% now choose oral risdiplam over intrathecal nusinersen. Spinal muscular atrophy is a motor neuron...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
GCC SPINAL MUSCULAR ATROPHY DISEASE LANDSCAPE

Saudi Arabia sees 200-250 new SMA births a year, yet a legacy cohort of 800-1,200 GCC patients remains ineligible for gene therapy entirely. Spinal muscular...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US SICKLE CELL DISEASE DISEASE LANDSCAPE

Sickle cell disease cuts US median life expectancy to about 54 years, a 22-year gap, yet hydroxyurea still reaches only a quarter of eligible patients. Sickle cell...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
UK SICKLE CELL DISEASE DISEASE LANDSCAPE

NICE's Casgevy recommendation (TA1044) carries a £300-600 million annual NHS exposure across just 200-300 eligible severe patients a year. Sickle cell disease is...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
GCC SICKLE CELL DISEASE DISEASE LANDSCAPE

Saudi Arabia alone carries an estimated 140,000-200,000 sickle cell patients, while mandatory premarital screening cuts new HbSS births 15-20% a year. Sickle cell...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US PSORIASIS DISEASE LANDSCAPE

Psoriasis affects 7.55 million US adults, yet only one in five carries the moderate-to-severe disease that reaches biologics. Psoriasis prevalence among US adults...

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