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@moatrx • 2 weeks ago

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@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
GCC MYASTHENIA GRAVIS DISEASE LANDSCAPE

Just 8-10 GCC neurologists manage 70-80% of confirmed myasthenia gravis, yet 30-40% are first misdiagnosed as thyroid myopathy. Myasthenia gravis affects an...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US MASH DISEASE LANDSCAPE

US MASH's commercial pool is not the 86.3 million with fatty liver; it is the 6.7 million with F2-F3 fibrosis, and most are unstaged. MASH is the progressive,...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US IGA NEPHROPATHY DISEASE LANDSCAPE

IgA nephropathy is the most common primary glomerulonephritis, yet it had no disease-specific therapy until 2021, and 30-40% of patients still progress to kidney...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
UK IGA NEPHROPATHY DISEASE LANDSCAPE

IgA nephropathy drives 10-12% of incident UK end-stage renal disease, a burden NICE built into its budesonide and sparsentan case. IgA nephropathy is an...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
GCC IGA NEPHROPATHY DISEASE LANDSCAPE

GCC nephrologists biopsy fewer than 30% of eligible proteinuric patients, versus roughly 70% in Japan and Germany, masking IgAN. IgA nephropathy is estimated to...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US HEREDITARY ANGIOEDEMA DISEASE LANDSCAPE

One in 50,000 Americans has HAE, yet laryngeal attacks are just 0.9% of episodes and still drive nearly all its mortality. Hereditary angioedema is an...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
UK HEREDITARY ANGIOEDEMA DISEASE LANDSCAPE

NICE TA606 lanadelumab cut UK HAE attack frequency from 12 a year to 1.5, an 87% reduction. Hereditary angioedema is a genetic disorder of the complement and kinin...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
GCC HEREDITARY ANGIOEDEMA DISEASE LANDSCAPE

KFSH&RC's HAE registry finds 3.8 relatives per index case, double Europe's rate, yet fewer than 200 GCC patients are confirmed. Hereditary angioedema is an...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US GAUCHER DISEASE DISEASE LANDSCAPE

Gaucher type 1 concentrates in the Ashkenazi Jewish founder population at 1 in 500-1,000, and the same genotype carries a near 20-fold Parkinson's risk. Gaucher...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
US FABRY DISEASE DISEASE LANDSCAPE

Fabry disease has two faces: a classic childhood form, and a later-onset cardiac form that is far more common, yet mostly undiagnosed. Fabry disease is an X-linked...

@moatrx • 2 weeks ago • comments: 0

Posted a new blog:
UK FABRY DISEASE DISEASE LANDSCAPE

The UK Fabry Outcome Survey tracks roughly 600 of the UK's estimated 800 diagnosed Fabry patients longitudinally. Fabry disease is an X-linked lysosomal storage...

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